Seminars

June 05, 2020: M.D. Vu Thi Hanh (Bach Mai Hospital), Application of biomedical image analysis in cytogenetic tests of hematology malignant diseases

Hematology malignant diseases such as Leukemia, Lymphoma, and Multiple Myeloma are serious illnesses. The estimated number of new cases of Chronic Myeloid Leukemia (CML), according to the report by WHO in 2014, is 1-2/100k people annually. Without diagnostics and treatment with targeted drugs, most CML patients with acute Leukemia would only live a few months. Targeted therapy for CML patients in early-stage with a positive response could reach life expectancy up to 10 years more. In diagnostics and analysis of hematology malignant, according to WHO classiﬁcation standard, cytogenetic tests such as karyotyping of the chromosomes image of the bone marrow cells and Fluorescence in situ hybridization (FISH) act an important role. In this talk, I would like to present the background of the hematology malignant diseases, chromosomal abnormality analysis procedure using karyotyping and FISH techniques. However, the results often prolong to 7-10 days because the current technology requires a lot of manual techniques, which results in delayed therapy treatment. Therefore, automatization in image analysis procedure in karyotyping and FISH is necessary for early diagnostics and treatment of the hematology malignant diseases.

Speaker: M.D. Vu Thi Hanh, Bach Mai Hospital

Time: 15:30, Friday, June 05, 2020

Venue: G2-315, 144 Xuan Thuy, Cau Giay, Hanoi

Vu Thi Hanh is currently the chief of the Genetic and Molecular Biology Laboratory of Hematology and Blood Transfusion Department, Bach Mai Hospital. Her job specializes in analyzing human chromosome abnormality and detecting mutation genes in hematology malignant such as leukemia, myeloproliferative neoplasm diseases. She received a Bachelor of Medical Technology at Hanoi Medical University in 2008. She has been working for Bach Mai Hospital since 2008. She completed a Master Program at College Medicine, Taipei Medical University, Taiwan in 2018, focusing on antiemetic metoclopramide and dengue virus infection.

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